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Screening von Tizanidin (Sirdalud)

Screening of Tizanidin (Sirdalud)

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  • Lebensmittel, Pharmaka und Pesticiden
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Summary

Tizanidin, a new muscle relaxant which undergoes intensive biotransformation, can easily be screened by UV-photometry after extraction from alkaline medium with ethyl acetate. Absorption maxima in the range of 310 nm and 321 nm, respectively, could be observed in more than 60 cases after the ingestion of therapeutical doses. Other commonly used muscle relaxants such as baclofen, chlormezanon and tetrazepam revealed no maxima in this range.

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Authors and Affiliations

  1. Institut für Rechtsmedizin der Universität, Frankfurter Strasse 58, D-6300, Gießen, Bundesrepublik Deutschland

    Harald Schütz, Annette Borchert, Wolf -Rüdiger Schneider & Klaus Schölermann

Authors
  1. Harald Schütz
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  2. Annette Borchert
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  3. Wolf -Rüdiger Schneider
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  4. Klaus Schölermann
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Additional information

5-Chlor-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazol

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Schütz, H., Borchert, A., Schneider, W.R. et al. Screening von Tizanidin (Sirdalud). Z. Anal. Chem. 328, 112–113 (1987). https://doi.org/10.1007/BF00560962

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  • DOI: https://doi.org/10.1007/BF00560962

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