Abstract
A genetic variation was found in pancreatic proteinase of Japanese quail. In eight bands of proteinase isozymes, the variation of band 5 (presence or absence) was detected among quails. Band 5 was identified as a chymotrypsin. The presence and absence of band 5 are controlled by a pair of allelic genes (Prt-5 A andPrt-5 a) on an autosomal locus, and genePrt-5 A, causing expression of band 5, is dominant to genePrt-5 a, a null allele for band 5. Zymograms of proteinases and their zymogens were also compared; no variation of chymotrypsinogen; corresponding to chymotrypsinPrt-5 was detected. It is suggested that thePrt-5 variant of chymotrypsin may be formed during activation of chymotrypsinogen.
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Hou, DX., Maeda, Y., Okamoto, S. et al. Genetic studies on pancreatic proteinase in Japanese quail. Biochem Genet 27, 469–479 (1989). https://doi.org/10.1007/BF00553913
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DOI: https://doi.org/10.1007/BF00553913