Summary
A patient is presented who developed a diffuse mixed lymphoma after successful treatment of small cell undifferentiated carcinoma of the lung. The patient was treated with cytotoxic chemotherapy and irradiation for the lung cancer, and had no recurrence during 6 years with no treatment. He then developed stage IV lymphoma. The relationship between these two cancers and the occurrence of treatment-induced second malignancies in small cell carcinoma are discussed.
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Armitage JO, Dick FR, Goeken JA, Foucarm K, Gingrich RD (1983) Second lymphoid malignancies occurring in patients treated for Hodgkin's disease. Arch Intern Med 143:445–450
Grünwald HW, Rosner F (1982) Acute myeloid leukemia following treatment of Hodgkin's disease. A review. Cancer 50:676–683
Krikorian JG, Burke JS, Rosenberg SA, Kaplan HS (1979) Occurrence of non-Hodgkin's lymphoma after therapy for Hodgkin's disease. N Engl J Med 300:452–458
Markman M, Pavy MD, Abeloff MD (1982) Acute leukemia following intensive therapy for small-cell carcinoma of the lung. Cancer 50:672–675
Mukherji B, Yamase HT (1983) Acute leukemia developing after intensive chemotherapy for small cell cancer of the lung. Cancer Treat Rep 67:100–101
Newcomer LN, Farber LR (1982) Acute myelogenous leukemia after successful treatment of small cell carcinoma of the lung. South Med J 75:80–81
Portugal MA, Falkson HC, Stevens K, Falkson G (1979) Acute leukemia as a complication of long-term treatment of advanced breast cancer. Cancer Treat Rep 63:177–181
Reimer RR, Hoover R, Fraumeni JF, Young RC (1977) Acute leukemia after alkylating-agent therapy of ovarian cancer. N Engl J Med 297:177–181
Rose VL, Keppen MD, Eichner ER, Pitha JV, Murray JL (1983) Acute leukemia after successful chemotherapy for oat cell carcinoma. Am J Clin Pathol 79:122–124
Rosner F, Grünwald HW, Zarrabi MH (1979) Acute leukemia as a complication of cytotoxic chemotherapy. Int J Radiat Oncol Biol Phys 5:1705–1707
Vogelzang NJ, Arthur D, Kennedy BJ (1982) Leukemia occurring after treatment of small cell lung cancer. Cancer Treat Rep 66:1683–1684
Weiss RB, Minna JD, Glatstein E, Martini N, Ihde DC, Muggia FM (1980) Treatment of small cell undifferentiated carcinoma of the lung: update of recent results. Cancer Treat Rep 64:539–548
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Weiss, R.B., Klein, M.A. Non-hodgkin's lymphoma after successful therapy of small cell lung carcinoma. Cancer Chemother. Pharmacol. 14, 9–11 (1985). https://doi.org/10.1007/BF00552716
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DOI: https://doi.org/10.1007/BF00552716