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Antonie van Leeuwenhoek

, Volume 58, Issue 3, pp 137–146 | Cite as

A review of the role of 70 kDa heat shock proteins in protein translocation across membranes

  • Elizabeth Craig
  • Pil Jung Kang
  • Will Boorstein
Article

Summary

The compartmentalization of essential hsp70 proteins indicates that hsp70s carry out crucial functions in several compartments of the cell. The use of conditional mutants has allowed study of the cellular processes that require hsp70 function. For efficient translocation of proteins across membranes hsp70s are required in the cytoplasm, as well as in the matrix of mitochondria and in the lumen of the endoplasmic reticulum.

Keywords

Endoplasmic Reticulum Heat Shock Heat Shock Protein Cellular Process Hsp70 Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1990

Authors and Affiliations

  • Elizabeth Craig
    • 1
  • Pil Jung Kang
    • 1
  • Will Boorstein
    • 1
  1. 1.Department of Physiological ChemistryUniversity of Wisconsin-MadisonMadisonUSA

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