Journal of Materials Science

, Volume 24, Issue 12, pp 4261–4264 | Cite as

Growth and characterization of 2-(meta-methoxyphenyl) thiazolidine

  • K. S. Raju
  • S. Eswaramoorthy
  • R. Umarani
  • P. Rajalingam


2-(meta-methoxyphenyl) thiazolidine (hereafter called 2mmpT) has medicinal importance, as the five-membered thiazolidine ring happens to be the active part of penicillin. This material has been synthesized and crystallized. The crystals are needle-shaped and of dimensions 0.3 × 0.5 × 1.5mm3 using X-ray diffraction technique, oscillation and Weissenberg patterns of the sample are taken. It is shown that the crystal is monoclinic and the unit cell parameters are found to be a = 1.007(5) nm, b=0.545(3) nm, c=1.720(8) nm and β=71.3(3)°. The space group is P21/c.

From IR absorption spectrum of the sample, the characteristic peak pertaining to NH at 3250cm−1 has been identified. The proton magnetic resonance (PMR) spectrum of the sample unambiguously supports the proposed structure of the compound. It has been confirmed that thiazolidine complex in the present case is a cyclic and not a linear one. The implications are discussed.


Polymer Proton Magnetic Resonance Absorption Spectrum Penicillin Characteristic Peak 
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  1. 1.
    V. G. Yokovlev, “Chemical protection of the body against ionising radiation”, edited by V. S. Balabukha (Pergamon Press, New York, 1963) p. 11.Google Scholar
  2. 2.
    J. F. Thomson (Reinhold, New York, 1962) p. 84.Google Scholar
  3. 3.
    V. M. Kulkarni and G. Govil, J. Pharm. Soc. 66 (1977) 483.Google Scholar
  4. 4.
    F. YU. Rachinskii, Akad. Nauk. SSSR 4 (1964) 256.Google Scholar
  5. 5.
    Dubs, P. Kuentzel and Heiner, US Patent 4011233.Google Scholar
  6. 6.
    United States Rubber Co. UK Patent 1059677.Google Scholar
  7. 7.
    V. G. Zubenko and M. M. Turkevich, Farmatsevt. Zh. 20 (1964) 3.Google Scholar
  8. 8.
    Yoshitomy Pharmaceutical Industries Ltd. Japan Kokai Tokkyo Koho Report 58174374.Google Scholar
  9. 9.
    Yoshitomy Pharmaceutical Industries Ltd. Japan Kokai Tokkyo Koho Report 5841872.Google Scholar
  10. 10.
    P. Main and M. M. Woolfson, Ada Crystallogr. 16 (1963) 731.Google Scholar
  11. 11.
    K. Nakamoto, “Infrared and Raman Spectra of Inorganic and Coordination Compounds”, 3rd Edn (Wiley, New York, 1978) p. 441.Google Scholar
  12. 12.
    J. R. Dyer, Applications of Absorption Spectroscopy of Organic Compounds, 3rd Edn (Prentice-Hall of India (P) Ltd, Delhi, 1974) pp. 30–31.Google Scholar

Copyright information

© Chapman and Hall Ltd 1989

Authors and Affiliations

  • K. S. Raju
    • 1
  • S. Eswaramoorthy
    • 1
  • R. Umarani
    • 2
  • P. Rajalingam
    • 2
  1. 1.Department of Crystallography and BiophysicsUniversity of MadrasMadrasIndia
  2. 2.Polymer DivisionCentral Leather Research InstituteAdyar, MadrasIndia

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