European Journal of Clinical Pharmacology

, Volume 26, Issue 5, pp 655–656 | Cite as

Amiodarone disposition: Polyexponential, power and gamma functions

  • G. T. Tucker
  • P. R. Jackson
  • G. C. A. Storey
  • D. W. Holt
Letters To The Editors

Key words

amiodarone statistical fitting power function gamma function polyexponential fits 

References

  1. Holt DW, Storey GCA, Jackson PR, Tucker GT, McKenna WJ (1983a) Amiodarone pharmacokinetics. Br J Clin Pharmacol 16: 206PGoogle Scholar
  2. Holt DW, Tucker GT, Jackson PR, Storey GCA (1983b) Amiodarone pharmacokinetics Am Heart J 106: 840–847Google Scholar
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  7. Sheiner LB (1983) ELSFIT Users manual. Technical report of the Division of Clinical Pharmacology, University of California at San FranciscoGoogle Scholar
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  9. Wise ME (1979) The need for rethinking on both compartments and modelling. In: Matis JH, Patten BC, White GC (eds) Compartmental analysis of ecosystem models. Int. Co-op. Publ House, Fairland, Maryland, USAGoogle Scholar
  10. Wise ME (1981) What should replace fitting of clearance values by sums of exponentials for compartmental analyses? 41st Int Congr Pharmaceut Sci, Vienna, Abstract 217Google Scholar
  11. Yamaoka K, Nakagawa T, Toyozo U (1978) Application of Akaike's Information Criterion (AIC) in the evaluation of linear pharmacokinetic equations. J Pharmacokinet Biopharm 6: 165–175Google Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • G. T. Tucker
    • 1
  • P. R. Jackson
    • 1
  • G. C. A. Storey
    • 2
  • D. W. Holt
    • 2
  1. 1.University Department of TherapeuticsRoyal Hallamshire HospitalSheffieldEngland
  2. 2.Poisons UnitGuy's HospitalLondonEngland

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