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Über die intercapilläre Glomerulosklerose bei Lebercirrhose

Intercapillary glomerulosclerosis in hepatic cirrhosis

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Summary

Quantitative morphologic studies on the glomeruli of kidneys from patients with cirrhosis of the liver revealed enlargement of the glomeruli and an increase in the mesangial matrix but no increase in the number of mesangial cells.

The glomerular changes in hepatic cirrhosis are called collectively “intercapillary glomerulosclerosis” because there is no proliferation of glomerular cells.

Zusammenfassung

Am Autopsiematerial von 30 Patienten untersuchten wir mit quantitativ-morphologischen Methoden die Frage nach den glomerulären Veränderungen bei verschiedenen Formen der Lebercirrhose. Es ergab sich eine Vergrößerung der Glomeruli und eine Zunahme des Mesangium. Die Mesangiumzellen sind nicht vermehrt. In Anbetracht des Fehlens einer Proliferation ortsständiger Zellen möchten wir die Veränderungen als intercapilläre Glomerulosklerose bezeichnen.

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Authors and Affiliations

  1. Pathologisches Institut der Universität Tübingen, Germany

    H. Wehner & D. Andler

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  1. H. Wehner
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  2. D. Andler
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Mit Unterstützung der Deutschen Forschungsgemeinschaft. Mit technischer Assistenz von Fräulein H. Huber.

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Wehner, H., Andler, D. Über die intercapilläre Glomerulosklerose bei Lebercirrhose. Virchows Arch. Abt. A Path. Anat. 360, 265–272 (1973). https://doi.org/10.1007/BF00542985

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  • DOI: https://doi.org/10.1007/BF00542985

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