Summary
The local effect of an aqueous suspension of beclomethasone dipropionate on human nasal mucociliary clearance was studied in 14 healthy volunteers. A triple blind, randomized, placebo controlled, cross-over design was utilised. Measurements of mucociliary clearance were made before treatment, after a single dose and after one week of continuous treatment either with placebo or active substance, utilising the saccharine-dye test. No change in mucociliary clearance was found after treatment with beclomethasone dipropionate or placebo suspension.
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Holmberg, K., Pipkorn, U. Influence of topical beclomethasone dipropionate suspension on human nasal mucociliary activity. Eur J Clin Pharmacol 30, 625–627 (1986). https://doi.org/10.1007/BF00542425
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DOI: https://doi.org/10.1007/BF00542425