Skip to main content
Log in

Utilization of antihypertensive drugs in certain European countries

  • Originals
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

Summary

The consumption of various groups of antihypertensive drugs in Spain during the period 1977–1981 has been measured by the DDD method. The total consumption of the drugs did not change much during this time. Combinations of thiazides with other hypotensives accounted for more than half the total antihypertensive drugs used. The consumption of rauwolfia and its derivatives, and of dihydralazine, was higher than of β-blockers and methyldopa. Total consumption of antihypertensives in 1981 was 37.5 DDDs/1 000 inhab/day, which was much lower than in Denmark (136.6 DDDs/1 000 inhab/day), Finland (114.5), Iceland (92.2), Norway (89.4) and Sweden (138.7). Wide qualitative differences between countries were also identified. Although other factors may play a role, it is suggested that these striking differences may be due to differences in general health policy and in the pharmaceutical markets.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Consejo General de Colegios Oficiales de Farmacéuticos (1982). Catálogo de Especialidades Farmacéuticas 1982. CGCOF Madrid

  2. Nordic Council on Medicines (1979) Nordic statistics on medicines 1975–1977, part II. Nordiska läkemedelsnämnden, Oslo

    Google Scholar 

  3. Lunde PKM, Baksaas I, Halse M, Halvorsen IK, Strømmes B, Øydvin K (1979) The methodology of drug utilization studies. In: Bergman U, Grimsson A, Wahba AHW, Westerholm B (eds) Studies in drug utilization. WHO Regional Office for Europe, Copenhagen, pp 17–28

    Google Scholar 

  4. Norsk Medisinaldepot (1980) Legemiddelforbruket I Norge. MND, Oslo

    Google Scholar 

  5. Laporte JR, Capellà D, Gisbert R, Porta M, Frati ME, García Santesmases MP, García Iñesta A (1981) The utilization of sedative-hypnotic drugs in Spain. In: Tognoni G, Bellantuono C, Lader M (eds) Epidemiological impact of psychotropic drugs. Elsevier/North-Holland, Amsterdam, pp 137–49

    Google Scholar 

  6. Consejo General de Colegios Oficiales de Farmacéuticos (1978) La oficina de farmacia en España. CGCOF, Madrid

    Google Scholar 

  7. Bonal J, Altimiras J, Cánovas P, Gisbert R (1980) La contaminació per medicaments. In: Congrés de Metges i Biòlegs de Llengua Catalana, 2a Ponència: Ecologia i Salut. Acadèmia de Ciències Mèdiques de Catalunya i de Balears, Barcelona, pp 253–61

    Google Scholar 

  8. Anonimous (1978) Los 500 medicamentos de mayor consumo en el año 1977. Mundo Farmacéutico 5: 215–254

    Google Scholar 

  9. Hodge JV, McQueen EG, Smirk FH (1960) Results of hypotensive therapy in arterial hypertension. Based on experience with 497 patients treated and 156 controls, observed for periods of one to eight years. Br Med J 1: 1–5

    Google Scholar 

  10. Breckenridge A, Dollery CT, Parry EHO (1970) Prognosis of treated hypertension. Quart J Med 39: 411–5

    Google Scholar 

  11. Veterans Administration Cooperative Study Group on Antihypertensive Agents (1970). Effect of treatment on morbidity in hypertension. II. Results in patients with diastolic blood pressure averaging 90 through 114 mmHg. J Am Med Assoc 213: 1143–52

    Google Scholar 

  12. Management Committee of the Australian Hypertension Trial (1979) Initial results of the Australian Therapeutic Trial in Mild Hypertension. Clin Sci 57 [Suppl]: 449S-452S

    Google Scholar 

  13. Helgeland A (1980) Treatment of mild hypertension: A five year controlled drug trial: The Oslo Study. Am J Med 69: 725–32

    Google Scholar 

  14. Freis ED (1982) Should mild hypertension be treated? N Engl J Med 307: 306–9

    Google Scholar 

  15. Gross F (1981) Drug utilization — theory and practice. The present situation in the Federal Republic of Germany. Eur J Clin Pharmacol 19: 387–94

    Google Scholar 

  16. Baksaas I (1978) Antihypertensive drugs. In: Duchêne-Marullaz P (ed) Advances in pharmacology and therapeutics, vol 6. Pergamon Press, New York, pp 133–41

    Google Scholar 

  17. Baksaas I, Fugelli P, Halvorsen IK, Lunde PKM, Naess K (1978) Prescription of hypotensives in general practice. Eur J Clin Pharmacol 14: 309–17

    Google Scholar 

  18. Hedstrand H, Åberg H (1976) Detection and characterization of middle-aged men with hypertension. Acta Med Scand 199: 273–80

    Google Scholar 

  19. Prineas RJ, Stephens WB, Lovell RRH (1973) Blood pressure and its treatment in a community. The Albury blood pressure study. Med J Austr 1: 5–9

    Google Scholar 

  20. World Health Organization European Collaborative Group (1980) Multifactorial trial in the prevention of coronary heart disease: 1. Recruitment and initial findings. Eur Heart J 1: 73–80

    Google Scholar 

  21. Pardell H, Gasulla JM, Armario P, Hernández R (1983). Prevalencia de la hipertensión arterial en Hospitalet de Llobregat (Barcelona). Med Clin (Barcelona) 81: 553–7

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Capellà, D., Porta, M. & Laporte, J.R. Utilization of antihypertensive drugs in certain European countries. Eur J Clin Pharmacol 25, 431–435 (1983). https://doi.org/10.1007/BF00542106

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00542106

Key words

Navigation