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Rheumatology International

, Volume 6, Issue 2, pp 61–62 | Cite as

Rheumatoid factors in Ro (SSA) positive and Ro (SSA) negative rheumatoid arthritis patients

  • A. E. Gharavi
  • F. N. Skopouli
  • B. M. Patel
  • G. R. V. Hughes
  • H. M. Moutsopoulos
Originals

Summary

In this report increased IgA and IgM rheumatoid factors were detected in the saliva of Ro (SSA) rheumatoid arthritis patients by an isotype-specific radio-immunoassay.

Key words

Rheumatoid arthritis Sjögren's syndrome Antibodies to Ro (SSA) 

References

  1. 1.
    Moutsopoulos HM, Giotaki H, Maddison PJ, Mavridis AK, Drosos AA, Skopouli FN (1984) Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro (SSA) antibody a posible marker of penicillamine-D intolerance. Ann Rheum Dis 43:285–287Google Scholar
  2. 2.
    Moutsopoulos HM, Skopouli FN, Sarras AK, Tsampoulas K, Mavridis AK, Constantopoulos SH, Maddison PJ (1985) Anti-Ro (SSA) positive rheumatoid arthritis (RA): a clinico-serological group of patients with high incidence of penicillamine-D side effects. Ann Rheum Dis 44:215–219Google Scholar
  3. 3.
    Elkon KB, Caeiro F, Gharavi AE, Patel BM, Ferjencik PP, Hughes GRV (1981) Radioimmunoassay profile of antiglobulins in connective tissue diseases: elevated level of IgG antiglobulin in systemic sicca syndrome. Clin Exp Immunol 46:547–556Google Scholar
  4. 4.
    Reichlin M, Maddison PJ (1979) Soluble tissue autoantigens which precipitate with sera of patients with connective tissue disease. In: Beutner EH (ed). Immunopathology of the skin. Wiley, New York, pp 357–362Google Scholar
  5. 5.
    Tarpley TM, Anderson LG, White CL (1974) Minor salivary gland involvement in Sjögren's syndrome. Oral Surg 37:64–74Google Scholar
  6. 6.
    Elkon KB, Gharavi AE, Patel BM, Hughes GRV, Frankel A (1983) IgA and IgM rheumatoid factors in serum, saliva and other secretions: relationship to immunoglobulin ratios in systemic sicca syndrome and rheumatoid arthritis. Clin Exp Immunol 52:75–79Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • A. E. Gharavi
    • 1
  • F. N. Skopouli
    • 2
  • B. M. Patel
    • 1
  • G. R. V. Hughes
    • 1
  • H. M. Moutsopoulos
    • 2
  1. 1.Department of Medicine, Royal Postgraduate Medical SchoolHammersmith HospitalLondonUK
  2. 2.Department of Medicine, Medical SchoolUniversity of IoanninaIoanninaGreece

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