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The influence of haemodialysis and haemofiltration on the clearance of Torasemide in renal failure

  • G. Loute
  • A. Adam
  • P. Ers
  • C. Heremans
  • B. Willems
Article

Summary

The concentration of Torasemide in plasma, dialysate and ultrafiltrate were determined during one haemofiltration and three dialyses. Results show that Torasemide is not significantly eliminated from the blood by these technics.

Key words

torasemide renal failure haemodynamics clearance pharmacokinetics 

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Reference

  1. 1.
    Lesne M, Clerck-Braun F, Duhoux P, van Ypersele de Strihou Ch (1982) Pharmacokinetic study of torasemide in humans: An overview of its diuretic effect. Int J Clin Pharmacol Ther Toxicol 20 [8]: 382–387Google Scholar
  2. 2.
    Dodion L, Willems JL (1986) Study of the elimination kinetics of torasemide, a novel loop diuretic, in renal insufficiency. Eur J Clin Pharmacol 31 [Suppl]: 49–51Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • G. Loute
    • 2
  • A. Adam
    • 2
  • P. Ers
    • 2
  • C. Heremans
    • 2
  • B. Willems
    • 1
  1. 1.Departement de NéphrologieService de Médecine InterneBaconfoyBelgium
  2. 2.Laboratoire de Biologie CliniqueCentre Hospitalier de Sainte-OdeBaconfoyBelgium

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