Rheumatology International

, Volume 5, Issue 5, pp 239–240 | Cite as

Cyclophosphamide-induced remission in Weber-Christian panniculitis

  • W. Kirch
  • U. Dührsen
  • H. Hoensch
  • E. Ohnhaus
Case Report


A patient with Weber-Christian panniculitis is described in this report in which treatment with prednisone and hydroxychloroquine caused no improvement of the disease, and even led to a worsening of the symptoms. In contrast, administration of oral cyclophosphamide led to a rapid remission of the disease. As Weber-Christian disease has no known aetiology and no specific treatment has been established, the successful therapy with the cytostatic drug cyclophosphamide may shed light on the pathogenesis of Weber-Christian panniculitis.

Key words

Weber-Christian panniculitis Cyclophosphamide Remission 


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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • W. Kirch
    • 1
  • U. Dührsen
    • 1
  • H. Hoensch
    • 1
  • E. Ohnhaus
    • 1
  1. 1.Department of MedicineUniversity of EssenEssenGermany

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