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European Journal of Pediatrics

, Volume 142, Issue 4, pp 306–307 | Cite as

Familial haemophagocytic lymphohistiocytosis in two brothers: Possible relationship between impaired immune function and clinical picture of graft-versus-host disease

  • N. Rascio
  • M. Duse
  • G. L. Marseglia
  • L. Nespoli
  • A. G. Ugazio
Letters to the Editors

Key words

Graft-versus-host disease Familial haemophagocytic lymphohistiocytosis 

Abbreviations

FHL

familial haemophagocytic lymphohistiocytosis

GVHD

graft-versus-host disease

References

  1. 1.
    Barth RF, Vergara GG, Khurana SK, Lowman JT, Beckwith JB (1972) Rapidly fatal familial histiocytosis with eosinophilia and primary immunological deficiency. Lancet 2:503–506Google Scholar
  2. 2.
    Beck J-D, Weinig, JE, Müller-Hermelink HK, Lemmel EM (1977) Reversible graft versus host reaction as cause of erythrophagic splenomegaly in a child? Eur J Pediatr 126:175–184Google Scholar
  3. 3.
    Blennow G (1974) Hemophagocytic reticulosis. Arch Dis Child 49:960–963Google Scholar
  4. 4.
    Janka GE (1983) Familial hemophagocytic lymphohistiocytosis Eur J Pediatr 140: 221–230Google Scholar
  5. 5.
    Ladish S, Poplack DG, Holiman B, Blaese RM (1978) Immunodeficiency in familial erythrophagocytic lymphohistiocytosis. Lancet 1:581–583Google Scholar
  6. 6.
    Nezelof C, Elichar E (1973) La lymphohistiocitose familiale. Revue général à propos de trois observations. Liens éventuels avec les syndromes secondaires. Nouv Rev Fr Hématol 13:319–337Google Scholar
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    Ochs HD, Davis SD, Mickelson E, Lerner KG, Wegwood RJ (1974) Combined immunodeficiency and reticuloendotheliosis with eosinophilia. J Pediatr 85:463–465Google Scholar
  8. 8.
    Omenn GS (1965) Familial reticuloendotheliosis with eosinophilia. New Engl J Med 273:427–432Google Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • N. Rascio
    • 1
  • M. Duse
    • 1
  • G. L. Marseglia
    • 1
  • L. Nespoli
    • 1
  • A. G. Ugazio
    • 1
  1. 1.Department of PediatricsUniversity of PaviaPaviaItaly

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