European Journal of Pediatrics

, Volume 142, Issue 4, pp 292–295 | Cite as

Oral chloramphenicol therapy for multiple liver abscesses in hyperimmunoglobulinemia E syndrome

  • S. Fanconi
  • R. A. Seger
  • U. Willi
  • R. Otto
  • H. Spiess
  • F. H. Kayser
  • W. H. Hitzig
Case Reports


In a patient with Hyper-IgE-syndrome multiple liver abscesses developed in spite of prophylactic treatment with trimethoprim and sulfamethoxazol. Ultrasound confirmed the clinical diagnosis and percutaneous needle aspiration under ultrasonographic guidance and culture of the aspirated pus allowed specific antibiotic treatment by oral chloramphenicol alone without surgical drainage. The isolated Staph. aureus strain was resistant to trimethoprim and sulfamethoxazol.

Key words

Hyper-IgE-syndrome Multiple liver abscesses Percutaneous needle aspiration Oral chloramphenicol 


Staphylococcus aureus

Candida albicans






artificial respiration


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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • S. Fanconi
    • 1
  • R. A. Seger
    • 1
  • U. Willi
    • 1
  • R. Otto
    • 2
  • H. Spiess
    • 3
  • F. H. Kayser
    • 4
  • W. H. Hitzig
    • 1
  1. 1.Department of Pediatrics, Divisions of Hematology-Immunology and of RadiologyUniversity ZürichZürichSwitzerland
  2. 2.Department of RadiologyUniversity of ZürichZürichSwitzerland
  3. 3.Neuroradiologisches InstitutZürich
  4. 4.Department of Medical MicrobiologyUniversity of ZürichZürichSwitzerland

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