The Italian Journal of Neurological Sciences

, Volume 19, Supplement 6, pp S399–S402 | Cite as

Contribution of magnetic resonance imaging techniques in understanding cognitive impairment in multiple sclerosis

  • M. Filippi
Cognitive Dysfunction In MS


In this review, the results of recent quantitative magnetic resonance imaging (MRI) studies correlating the degree of cognitive impairment in multiple sclerosis patients with the extent and severity of brain abnormalities seen using MRI techniques are presented and discussed with the ultimate goal of a better understanding of the pathophysiological mechanisms underlying the development of such deficits.

Key words

Multiple sclerosis Magnetic resonance imaging Cognitive functions Magnetization transfer imaging Frontal lobe 


In questa revisione della letteratura, vengono presentati e discussi i risultati di recenti studi di risonanza magnetica (RM) quantitativa nei quali il grado di deficit cognitivo in pazienti affetti da sclerosi multipla e stato correlato con l'estensione e la gravity delle alterazioni encefaliche evidenziate con tecniche differenti di RM, al fine di raggiungere una migliore comprensione dei meccanismi patogenetici sottesi allo sviluppo di tall deficit.


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Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • M. Filippi
    • 1
  1. 1.Neuroimaging Research Unit Department of Neuroscience Scientific Institute Ospedale San RaffaeleUniversity of MilanoMilanoItaly

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