Skip to main content
SpringerLink
Log in

Research on naphthyridines. 10. Synthesis and ionization constants of 10-alkylaminobenzo[b]-1,8-naphthyridines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

10-Alkylaminobenzo[b]-1,8-naphthyridines were synthesized by cyclization of 2-arylaminonicotinic acid alkylamides by means of phosphorus oxychloride. The pKal values of the 10-alkylaminobenzo[b]-1,8-naphthyridines, which range from 8.74 to 8.50, were determined by potentiometric titration in anhydrous ethanol.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. A. I. Mikhalev and M. E. Konshin, Khim. Geterotsikl. Soedin., No. 9, 1241 (1977).

    Google Scholar 

  2. V. P. Chesnokov and M. E. Konshin, Khim. Geterotsikl. Soedin., No. 2, 247 (1974).

    Google Scholar 

  3. A. I. Mikhalev, V. K. Kudryashova, V. S. Zalesov, V. P. Chesnokov, and M. E. Konshin, Khim.-Farm. Zh., No. 11, 78 (1977).

    Google Scholar 

  4. F. V. Mason, J. Chem. Soc., No. 9, 4874 (1957).

    Google Scholar 

  5. I. V. Persianova, Yu. N. Sheinker, R. M. Titkova, and A. S. Elina, Khim. Geterotsikl. Soedin., No. 7, 965 (1977).

    Google Scholar 

  6. R. M. Acheson, Acridines, Vol. 9, New York-London (1956), p. 339.

    Google Scholar 

  7. A. Albert and E. Serjeant, Ionization Constants of Acids and Bases, Methuen (1962).

Download references

Author information

Authors and Affiliations

  1. Perm Pharmaceutical Institute, 614600, Perm

    A. I. Mikhalev, V. P. Chesnokov & M. E. Konshin

Authors
  1. A. I. Mikhalev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. P. Chesnokov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. E. Konshin
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

See [1] for communication 9.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 799–801, June, 1979.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mikhalev, A.I., Chesnokov, V.P. & Konshin, M.E. Research on naphthyridines. 10. Synthesis and ionization constants of 10-alkylaminobenzo[b]-1,8-naphthyridines. Chem Heterocycl Compd 15, 652–653 (1979). https://doi.org/10.1007/BF00539502

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00539502

Keywords

Search

Navigation