Effect of ivermectin against subperiodic Brugia malayi infection in the leaf monkey, Presbytis cristata
Invermectin at single doses of 0.2–1.0 mg/kg body weight reduced the microfilarial counts of subperiodic Brugia malayi in Presbytis cristata by 59.9%–89.6% of initial counts, 4 weeks after treatment. Adult filaricidal activity was poor, live adult worms being recovered from all animals at autopsy. There was no serious side effect at these doses.
KeywordsBody Weight Single Dose Adult Worm Ivermectin Initial Count
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