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Corticoid-Therapie bei akuten Vergiftungen durch Carbaryl und phosphorhaltige Pesticide

Therapy with corticosteroid compounds in acute poisoning with carbamate and organophosphate pesticide

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Summary

Twenty five cases of poisoning with organophosphate and Carbamate (Sevin®) compounds treated with different Corticosteroids are described. Most of the patients suffered from professional intoxications and some other cases had accidental poisoning.

With the exception of one patient who died with pulmonary edema and circulatory disturbances all the other cases had an uncomplicated restitution “ad integrum”.

The efficiency of corticoids as causal treatment in poisoning with organophosphates and Carbamate (Sevin®) is discussed with the particular symptomatology of the kind of intoxication.

Zusammenfassung

Bei 25 Patienten mit akuter Vergiftung durch Carbaryl und phosphorhaltige Pesticide, die meistens beruflich, in einigen FÄllen akzidentell bedingt war, wurde eine kausale Behandlung mit verschiedenen Corticoiden vorgenommen.

Mit Ausnahme eines Patienten, der 11 Std nach Beginn der Therapie infolge eines Lungenödems und Kreislaufversagens verstarb, trat bei allen Patienten eine vollkommene Heilung selbst nach schwerer Intoxikation innerhalb von maximal 19 Std ein. Die Wirksamkeit von Corticoiden als kausales Therapeuticum bei Vergiftungen durch Carbaryl und phosphorhaltige Pesticide wird durch die Ergebnisse dieser Untersuchung dargelegt.

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Authors and Affiliations

  1. Institut für Arbeitsmedizin der UniversitÄt des Saarlandes, Deutschland

    C. López

  2. Malstatterstr. 17, D-6600, Saarbrücken 1

    C. López

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  1. C. López
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Herrn Privatdozent Dr. H. Drasche danke ich für seine Hilfe bei der redak-tionellen Bearbeitung des deutschen Textes.

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López, C. Corticoid-Therapie bei akuten Vergiftungen durch Carbaryl und phosphorhaltige Pesticide. Int. Arch. Arbeitsmed 26, 50–62 (1970). https://doi.org/10.1007/BF00539234

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  • DOI: https://doi.org/10.1007/BF00539234

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