Abstract
Dominant megacolon (Dom) is one of four mutations in the mouse that can produce a phenotype similar to Hirschsprung disease in human. The Dom gene product is not known, and no candidate region has been defined for a possible human homolog. In this publication we report mapping the Dom locus with high definition, using several intra- and interspecific crosses and a set of 16 Chr 15-specific microsatellites flanking this locus.
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Puliti, A., Prehu, M.O., Simon-Chazottes, D. et al. A high-resolution genetic map of mouse Chromosome 15 encompassing the Dominant megacolon (Dom) locus. Mammalian Genome 6, 763–768 (1995). https://doi.org/10.1007/BF00539000
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DOI: https://doi.org/10.1007/BF00539000