Summary
The chest radiograms and the arterial \({\text{P}}_{{\text{O}}_{\text{2}} }\) values were studied in 61 patients suffering from severe acute CO poisoning. 22 patients (36.1%) showed abnormalities on chest film taken at the time of admission. The radiologic pulmonary abnormalities were classified into three patterns: 1. ground glass density, 2. interstitial edema, and 3. intraalveolar edema.
Particular emphasis was placed on the diffuse, homogenous and hazy density like ground glass on chest films, as the patients who presented “ground glass density” showed marked hypoxemia at the time of admission. Clinical symptoms of pulmonary edema were manifested in 4 eases (6.6%) in this series of patients.
Pulmonary edema in acute CO poisoning is far commonner than previously considered, and possible mechanism to develop it was discussed.
Similar content being viewed by others
References
Anderson, R. F., Allensworth, D. C., Degroot, W. J.: Myocardial toxicity from carbon monoxide poisoning. Ann. intern. Med. 67, 1172–1182 (1967)
Asmussen, E., Knudsen, E. O. E.: Studies in acute but moderate CO-poisoning. Acta physiol. scand. 6, 67–78 (1943)
Bour, H., Tutin, M., Pasquier, P.: The central nervous system and carbon monoxide poisoning. I. Clinical data with reference to 20 fetal cases. Progr. Brain Res. 24, 1–30 (1967)
Fisher, A. B., Hyde, R. W., Baue, A. E., Reif, J. S., Kelly, D. E.: Effect of carbon monoxide on function and structure of the lung. J. appl. Physiol. 26, 4–12 (1969)
Kittredge, R. D.: Pulmonary edema in acute carbon monoxide poisoning. Amer. J. Roentgenol. 113, 680–681 (1971)
Meigs, J. W., Hughes, J. P. W.: Acute carbon monoxide poisoning. An analysis of one hundred five cases. Arch. industr. Hyg. 6, 344–356 (1952)
Middleton, G. D., Ashby, D. W., Clark, F.: Delayed and long-lasting electro- cardiographic changes in carbon monoxide poisoning. Lancet 1961 I, 12–16
Niden, A. H., Schulz, H.: The ultrastructural effects of carbon monoxide inhalation on the rat lung. Virchows Arch. path. Anat. 339, 283–292 (1965)
Norman, J. N., Douglas, T. A., Smith, G.: Respiratory and metabolic changes during carbon monoxide poisoning. J. appl. Physiol. 21, 848–852 (1966)
Ogawa, M., Shimazaki, S., Tanaka, N., Ukai, T., Katsurada, K., Sugimoto, T.: Vascular permeability and blood volume changes in experimental carbon monoxide poisoning. Igaku-no-ayumi 84, 201–202 (1973)
Ogawa, M., Tamura, H., Katsurada, K., Sugimoto, T.: Respiratory changes in carbon monoxide poisoning with reference to hyperbaric oxygenation. Med. J. Osaka Univ. 22, 251–258 (1972)
Shafer, N., Smilay, M. G., MacMillan, F. P.: Primary myocardial disease in man resulting from acute carbon monoxide poisoning. Amer. J. Med. 38, 316–320 (1965)
Stearns, W. H., Drinker, C. K., Shaughnessy, T. J.: Electrocardiographic changes found in 22 cases of carbon monoxide (illuminating gas) poisoning. Amer. Heart J. 15, 434–447 (1938)
Takahashi, K.: Cardic disturbances due to CO poisoning in experimental animals. I. Electrocardiographic changes due to CO poisoning and those under the influences of fluid infusion. Tohoku J. exp. Med. 74, 211–223 (1961)
Takeya, H., Suzuki, K., Yoshida, T., Furukawa, K.: Hyperbaric oxygen therapy in carbon monoxide poisoning and experimental study. In: Hyperbaric medicine, Wada, J., Iwa, T., Eds., pp. 297–302. Tokyo: Igaku-shoin 1970
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ogawa, M., Katsurada, K., Sugimoto, T. et al. Pulmonary edema in acute carbon monoxide poisoning. Int. Arch. Arbeitsmed 33, 131–138 (1974). https://doi.org/10.1007/BF00538997
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00538997