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Localisation of the site of action of mersalyl, chlorothiazide and chlorthalidone in the renal tubule using the ischaemic stop flow technique

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Summary

The ischaemic stop flow technique was used to study the effect of mersalyl, chlorothiazide and chlorthalidone in the distal segment of the dog nephron. It was found that chlorothiazide and chlorthalidone inhibit the reabsorption of Na+ and Cl−, but that mersalyl has no demonstrable effect on the transport of either ion in this region.

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  1. Department of Medicine, The Queen's University of Belfast, Ireland

    J. McEvoy

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  1. J. McEvoy
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McEvoy, J. Localisation of the site of action of mersalyl, chlorothiazide and chlorthalidone in the renal tubule using the ischaemic stop flow technique. Naunyn-Schmiedebergs Arch. Pharmak. u. Exp. Path. 259, 314–318 (1968). https://doi.org/10.1007/BF00536905

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  • DOI: https://doi.org/10.1007/BF00536905

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