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The role of interleukin 2 (IL 2) in the proliferation of Theileria annulata-infected bovine lymphocytes

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Abstract

The role of interleukin 2 (IL 2) in the proliferation of Theileria annulata-infected lymphoblastoid cells was studied. It was found that these cells neither require nor produce IL 2. This was based on the following findings: (a) The growth of T. annulata-infected cells was not enhanced by addition of IL 2 to the culture medium, (b) IL 2-dependent Con A-stimulated bovine peripheral blood lymphocytes (Con A-blasts) no longer required IL 2 after being infected with sporozoites of T. annulata. (c) The supernatants of T. annulata-infected cells did not support growth of IL 2-dependent Con A-blasts.

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Authors and Affiliations

  1. Institut für Parasitologie und Tropenveterinärmedizin der Freien Universität Berlin, Königsweg 65, D-1000, Berlin 37

    J. S. Ahmed, S. Hauschild & E. Schein

Authors
  1. J. S. Ahmed
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  2. S. Hauschild
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  3. E. Schein
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Ahmed, J.S., Hauschild, S. & Schein, E. The role of interleukin 2 (IL 2) in the proliferation of Theileria annulata-infected bovine lymphocytes. Parasitol Res 73, 524–526 (1987). https://doi.org/10.1007/BF00535327

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  • DOI: https://doi.org/10.1007/BF00535327

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