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Chemistry of Heterocyclic Compounds

, Volume 29, Issue 5, pp 563–566 | Cite as

Research in the imidazole series. 94. Synthesis of derivatives of pyrrolo[1,2a]benzimidazolyl-4-acetic acid

  • P. M. Kochergin
  • R. M. Palei
  • S. A. Chernyak
Article
  • 31 Downloads

Abstract

Derivatives of pyrrolo[1,2a]benzimidazolyl-4-acetic add have been synthesized by quaternization of 2-alkyl(aralkyl)benzimidazolyl-1-acetic acids and their esters and amides by α-bromoketones, followed by cyclization of the resulting 1,2,3-substituted benzimidazolium bromides by the action of sodium alcoholate, ammonia, amines (primary, secondary, or tertiary), or hydrazine hydrate.

Keywords

Sodium Ammonia Ester Hydrate Bromide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • P. M. Kochergin
    • 1
  • R. M. Palei
    • 1
  • S. A. Chernyak
    • 1
  1. 1.All-Russian Scientific-Research Chemical-Pharmaceutical InstituteCenter for Chemistry of Pharmaceutical MaterialsMoscow

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