Abstract
It was established that on treatment with alkali, 2,5-disubstituted 3,3,4,4-tetracyanopyrrolidines react with primary alcohols to form 5-alkoxy-2-(N-arylidenamino)-3,4-dicyanopyrroles. Depending on the ratio of the initial reagents, another reaction route is possible, leading to 6-alkoxy-4-amino-2-R-3-CH2R-5-cyano-3H-pyrrolo[2,3-d]pyrimidines. The effect of substituents on the reaction pathways is examined.
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A. B. Zolotoi, A. N. Lyshchikov, P. M. Lukin, A. I. Prokhorov, O. E. Nasakin, A. Kh. Bulai, and L. O. Atovmyan, Dokl. Akad. Nauk SSSR, 313, 110 (1990).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1472–1476, November, 1992.
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Nasakin, O.E., Lyshchikov, A.N., Lukin, P.M. et al. Reactions of 3,3,4,4-tetracyanopyrrolidines with alcohols. Chem Heterocycl Compd 28, 1255–1259 (1992). https://doi.org/10.1007/BF00532072
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DOI: https://doi.org/10.1007/BF00532072