Summary
A new subline of the Yoshida sarcoma is characterized by 40 chromosome complex. Its specific idiogram is grossly distinguishable from the original line, as well as from the other sublines, by the presence of two unusually large V- and one J-shaped elements. The developmental course of the new subline, the change in transplantability and the life span of the tumor-bearing animals are recorded.
Zusammenfassung
Eine neue Unterlinie des Yoshida-Sarkoms weist Besonderheiten in ihrer Cytologie und anderen Eigenschaften auf. Ihre Zellen besitzen 40 Chromosomen und ein spezifisches Idiogramm leicht von der Originalline und anderen Unterlinien zu unterscheiden, und zwar hauptsächlich durch die Anwesenheit von 2 V- und ein J-förmiges besonders großes Chromosom. Der Entwicklungsablauf dieser Unterlinie, die Änderungen der Transplantabilität und die Lebenslänge eines tumortragenden Tieres sowie die Affinität der Tumorzellen zu verschiedenen Organen wird dargestellt. Das Yoshida-Sarkom kann also während der laufenden Übertragungen Änderungen seins Verhaltens sowie der Chromosomen mitmachen.
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With 12 figures in the text
Contributions from the National Institute of Genetics, Misima, Japan, No. 285.
Supported by a Grant from the Ministry of Education given for a Coordinating Research on “The mechanism of manifestation of gene” headed by Dr. Hitoshi Kihara of the National Institute of Genetics, Misima.
Read before the 49th Annual Meeting of the American Association for Cancer Research. Inc., on April 11, 1958, in Philadelphia, Pa., U.S.A.
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Yosida, T.H. Chromosomal alteration and the development of tumors. Zeitschrift für Krebsforschung 63, 209–214 (1959). https://doi.org/10.1007/BF00531591
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DOI: https://doi.org/10.1007/BF00531591