Chemistry of Heterocyclic Compounds

, Volume 28, Issue 9, pp 1070–1073 | Cite as

Synthesis and recyclization of 6-benzyl-3a,4,5,6,7,7a-hexahydro-3a-hydroxy-7a-methyl-2-thioxo-5-phenyloxazolo[5,4-c]pyridines

  • G. V. Pshenichnyi
  • V. A. Mashenkov


The corresponding oxazolo[5,4-c]pyridines were obtained in the reaction of stereoisomeric 1-benzyl-3-hydroxy-3-methyl-6-phenyl-4-piperidines with potassium thiocyanate in acetic acid and rearranged into 6-benzyl-5,6,7,8-tetrahydro-1-methyl-3-thioxo-7-phenyloxazolo[3,4-c]pyrimidine by boiling in o-xylene. It was shown that the rearrangement is reversible.


Acetic Potassium Acetic Acid Organic Chemistry Pyridine 


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Copyright information

© Plenum Publishing Corporation 1993

Authors and Affiliations

  • G. V. Pshenichnyi
    • 1
  • V. A. Mashenkov
    • 1
  1. 1.A. M. Gor'kii Minsk State Pedagogical InstituteMinsk

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