Synthesis, structure, and carbamoylation of 5-alkyl-N(1)-(β-hydroxyethyl)-4,5-dihydro-1,2,4-triazin-6-ones
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The condensation of methyl α-(dimethylaminomethyleneamino)alkanoates with β-hydroxyethylhydrazine gave the isomeric N(1)- and N(2)-(β-hydroxyethyl)-5-alkyl-4,5-dihydro-1,2,4-triazin-6-ones. It was shown by IR spectroscopy that the products exist in the form of betaines both in solution and in the crystalline state. The reaction of the N(1) isomers with alkyl and aryl isocyanates leads to the formation of mono- or dicarbamoyl-substituted triazines. The preferred reaction path involves carbamoylation of the β-hydroxyethyl group.
KeywordsSpectroscopy Methyl Organic Chemistry Betaine Isocyanate
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