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Synthesis of 4,5-bifunctionally substituted imidazolidin-2-ones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that the reaction of readily available 4,5-dihydroxyimidazolidin-2-ones with hydrazoic or p-toluenesulfinic acid takes place stereo- and regioselectively and leads to the formation of 4,5-diazido- or 4,5-di(p-tolylsulfonyl)imidazolidin-2-ones. The example of 4,5-diazidoimidazolidin-2-one is used to demonstrate the possibility of using compounds of this type for stereoselective introduction of substituents into the 4 and 5 positions of the imidazole ring.

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Authors and Affiliations

  1. M. V. Lomonosov Moscow State Academy of Fine Chemical Technology, 117571, Moscow

    A. D. Shutalev

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  1. A. D. Shutalev
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1645–1649, December, 1993.

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Shutalev, A.D. Synthesis of 4,5-bifunctionally substituted imidazolidin-2-ones. Chem Heterocycl Compd 29, 1421–1425 (1993). https://doi.org/10.1007/BF00531404

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  • DOI: https://doi.org/10.1007/BF00531404

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