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Reaction of 6-hydroxy-7,7-dicyclopropyl-5-oxaspiro[2,4] heptan-4-one and (1-formylcyclobutyl)-acetic acid with amines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 6-hydroxy-7,7-dicyclopropyl-5-oxaspiro[2,4]heptan-4-one and (1-formylcyclobutyl)acetic acid with amines may serve as a convenient method for the preparation of 5-(arylamino)tetrahydrofuran-2-ones. Treatment with diethylamine gave open-chain or cyclic compounds, depending upon the structure of the starting materials.

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Authors and Affiliations

  1. M. V. Lomonosov State University, 119899, Moscow

    A. G. Bessmertnykh, T. I. Voevodskaya, N. A. Donskaya & T. V. Zinevich

Authors
  1. A. G. Bessmertnykh
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  2. T. I. Voevodskaya
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  3. N. A. Donskaya
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  4. T. V. Zinevich
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1025–1030, August, 1992.

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Bessmertnykh, A.G., Voevodskaya, T.I., Donskaya, N.A. et al. Reaction of 6-hydroxy-7,7-dicyclopropyl-5-oxaspiro[2,4] heptan-4-one and (1-formylcyclobutyl)-acetic acid with amines. Chem Heterocycl Compd 28, 856–860 (1992). https://doi.org/10.1007/BF00531314

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  • DOI: https://doi.org/10.1007/BF00531314

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