Cell membrane changes of uterine epithelium and trophoblasts during blastocyst attachment in rat
The luminal cell membranes of both the trophoblasts and the uterine epithelium possessed microvilli during the pre-attachment stage, while these membranes lacked microvilli and had a tortous course during the attachment stage. The trophoblasts were separated from the uterine epithelium by a space of some tenths of a micron during the pre-attachment stage, while the luminal membranes of the cells were in a close contact during the attachment stage.
It was suggested that the mechanism of blastocyst attachment involved, i.a., an increased resorptive activity and an increased adhesiveness of the uterine epithelium, and that the structural differentiation of the trophoblasts was initiated by some factor in the uterine secretion.
KeywordsPublic Health Cell Membrane Luminal Close Contact Structural Differentiation
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