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Length of human constitutive heterochromatin in relation to chromosomal contraction

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Summary

Linear measurement of blocks of constitutive heterochromatin and the euchromatin portion 1q-h in three members of a family was used to study the dependence of the size of C blocks on the degree of chromosomal contraction. The results demonstrate that the size of heterochromatin portions decrease regularly with an increases of the degree of euchromatin contraction. The dependence was found to be linear, except for mitoses with an extremely high or low degree of contraction. The finding was used for the development of a new method of evaluation of constitutive heterochromatin.

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Authors and Affiliations

  1. Division of Medical Genetics, Department of Pediatrics, Faculty Hospital, 500 36, Hradec Králové, Czechoslovakia

    Petr Balíček, Jan Žižka & Hana Skalská

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  1. Petr Balíček
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  2. Jan Žižka
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  3. Hana Skalská
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Balíček, P., Žižka, J. & Skalská, H. Length of human constitutive heterochromatin in relation to chromosomal contraction. Hum Genet 38, 189–193 (1977). https://doi.org/10.1007/BF00527402

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  • DOI: https://doi.org/10.1007/BF00527402

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