Advertisement

Zeitschrift für Krebsforschung

, Volume 60, Issue 5, pp 597–608 | Cite as

Cytological studies of tumors

XV. Reciprocal effects on growth of two different tumors in the same host
  • Sajiro Makino
  • Akira Tonomura
Article

Summary

The present paper describes observations concerning the growth of two different rat ascites tumors, MTK-sarcoma II and Takeda sarcoma, implanted in the same host. Two types of tumor cells inoculated in the same host affect each other; the mitotic rate of the tumor cells is strikingly decreased and their damage with consequent retardation of tumor growth is remarkable. Growth of Takeda sarcoma is inhibited by either co-existence or pre-existance of MTK-sarcoma II in the same host. In the pre-existence of Takeda sarcoma, the damage to tumor cells of both tumors and consequent retardation of the tumor growth are very remarkable, prolonging the life of tumor-bearing animals in many cases.

Keywords

Public Health Tumor Cell Tumor Growth Cancer Research Sarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature

  1. 1.
    Isaka, H.: Gann 43, 287 (1952).Google Scholar
  2. 2.
    Graff, S., W. Antopol, G. Zagal and F. Agate: Cancer Res. 12, 383 (1952)Google Scholar
  3. 3.
    Makino, S., and K. Kanô: J. Nat. Canc. Inst. 13, 1213 (1953).Google Scholar
  4. 4.
    Makino, S., and T. Tanaka: J. Nat. Canc. Inst. 13, 1185 (1953a).Google Scholar
  5. 5.
    Makino, S., and T. Tanaka: Gann 44, 39 (1953b).Google Scholar
  6. 6.
    Satoh, H.: Gann 43, 270 (1952).Google Scholar
  7. 7.
    Takeda, K., M. Aizawa, T. Imamura, S. Sasage, K. Matsumoto and S. Kanehira: Gann 43, 132 (1952).Google Scholar
  8. 8.
    Tanaka, T., and K. Kanô: J. Fac. Sci. Hokkaido Univ., Ser. VI, Zool. 10, 289 (1951).Google Scholar
  9. 9.
    Tonomura, A.: J. Fac. Sci. Hokkaido Univ., Ser. VI, Zool. 11 (1954).Google Scholar
  10. 10.
    Yoshida, T. H.: Gann 45, 9 (1954).Google Scholar

Copyright information

© Springer-Verlag 1955

Authors and Affiliations

  • Sajiro Makino
    • 1
  • Akira Tonomura
    • 1
  1. 1.Zoological InstituteHokkaido UniversitySapporo(Japan)

Personalised recommendations