Zeitschrift für Krebsforschung

, Volume 64, Issue 4, pp 253–261 | Cite as

Cytological studies of tumors

XXXV. A study of chromosomes in venereal tumors of the dog
  • Susumu Takayama
  • Sajiro Makino
Article

Summary

The chromosome conditions were studied in five cases of venereal tumors of dogs found in different localities.

The data obtained indicate that four cases are characterized by the stemline chromosome-number of 59, while one is provided with two stem-lines, one at 59 and the other at 60. The ideogram analysis has revealed that the 59 (or 60) chromosomes consist of 16 metacentric chromosomes and 43 (or 44 in 60 cells) acrocentric ones. Since the normale somatic complement comprises 77 acrocentric chromosomes and a large metacentric one (X), the chromosomes of tumor cells differ grossly from the somatic elements both morphologically and numerically.

A remarkable karyological similarity of the stemline chromosomes occurring in several venereal tumors of dogs obtained from different localities was discussed on the basis of three possiblities.

Keywords

Public Health Tumor Cell Cancer Research Cytological Study Acrocentric Chromosome 

Zusammenfassung

In 5 Fällen von venerischen Tumoren von Hunden aus verschiedenen Gegenden Japans wurden die Chromosomenverhältnisse untersucht. In 4 Fällen sind die Zellen der Stammlinie gekennzeichnet durch 59 Chromosomen, 1 Fall wies zwei Stammlinien auf, nämlich eine zu 59 und eine zu 60 Chromosomen. Das Idiogramm zeigte, daß die 59 (oder 60) Chromosomen bestehen aus 16 metazentrischen und 43 (oder 44) akrozentrischen Chromosomen. Da die normale Chromosomenausstattung somatischer Zellen des Hundes (♂) aus 77 akrozentrischen und einem großen metazentrischen (X) Chromosom besteht, unterscheiden sich die Chromosomen des Tumors sehr wesentlich hinsichtlich Gestalt und Zahl von ihnen. Auch die karyologische Ähnlichkeit der Stammlinienchromosomen der verschiedenen venerischen Tumoren von Hunden aus verschiedenen Gegenden ist bemerkenswert

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Copyright information

© Springer-Verlag 1961

Authors and Affiliations

  • Susumu Takayama
    • 1
    • 2
  • Sajiro Makino
    • 1
    • 2
  1. 1.Biological LaboratoryKwansei Gakuin UniversityNishinomiaJapan
  2. 2.Zoological InstituteHokkaido UniversitySapporoJapan

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