Summary
The right common cardinal vein (Duct of Cuvier) was occluded by a silver clip in 220 chick embryos of three, three and a half, four and five days respectively. The swelling of the right cardinal veins caused by this operation gave rise to a swelling of the cardinal veins of the left side. Consequently the disappearance of the postcardinal veins was retarded. One to one and a half days after the operation collateral veins going round the clip were established. Thereby the circulatory situation as the development of the cardinal veins became normal.
In some of the embryos operated the fifth day the collateral vein was not found. The anterior cardinal and middle cerebral vein disappeared soon after the operation. The blood from the right half of the head and neck passed through a capillary network situated over the met- and myelencephalon and emptied into the left anterior cardinal vein. Since these embryos were no longer able to correct the circulation by establishing collateral veins they died within 24 hours.
After the fourth day the system of cardinal veins can accomodate itself to changed circulatory conditions for a short time but it has only in part the possibility of establishing the original situation.
Zusammenfassung
Bei 3-, 31/2, 4- und 5tägigen Hühnerembryonen (insgesamt 220) wurde der Ductus Cuvieri dexter mittels feinem Silberclip unterbrochen. Die dadurch bedingte massive Stauung in den Vv. cardinales dextrae übertrug sich auf die Kardinalvenen der linken Seite. Diese bildeten sich bei den älteren Stadien nur verzögert zurück. Im Laufe von einem bis anderthalb Tagen entstanden den Clip in der Regel caudal umgehende Kollateralvenen, worauf sich Kreislaufverhältnisse und Entwicklung normalisierten.
Bei einem Teil der am 5. Tag operierten Embryonen kam es nicht mehr zur Kollateralenbildung. Die Vv. cardinalis anterior et cerebri media obliterierten kurz nach dem Eingriff. Das Blut aus der rechten Kopf- und Halshälfte floß über ein dichtes Capillarnetz im Bereiche von Myel- und Metencephalon nach links ab. Infolge der nicht mehr korrigierbaren veränderten Zirkulation gingen diese Keime innert 24 Std zugrunde.
Vom 5. Tag an besitzt das Kardinalvenensystem noch in allen Fällen die Fähigkeit einer kurzfristigen Anpassung an neue Kreislaufverhältnisse, hingegen nur noch bedingt die Möglichkeit einer Reparation des veränderten Blutgefäßsystems.
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Müntener, M. Experimentelle Untersuchung der Kardinalvenenentwicklung bei 3–5tägigen Hühnerembryonen. Z. Anat. Entwickl. Gesch. 140, 351–365 (1973). https://doi.org/10.1007/BF00525061
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DOI: https://doi.org/10.1007/BF00525061