Advertisement

Zeitschrift für Krebsforschung

, Volume 67, Issue 3, pp 224–229 | Cite as

Mast cell response after homo- and heterologous grafts of tumoral and nontumoral origin

  • O. Costâchel
  • Mironescu
  • N. Stroescu
Article

Summary

Several types of solid grafts (tumoral and nontumoral, both of homo- and heterologous varieties) were performed. A growing tumor-implant (Jensen sarcoma) in Wistar rats is accompanied by a decrease of the mast cells in the surrounding connective tissue. Both degranulation and degenerative (granular clumping) processes of these cells could be observed. In the other types of grafts studies the mast cells alterations were less pronounced.

Keywords

Public Health Cancer Research Sarcoma Mast Cell Connective Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Ein im Bindegewebe von Wistar-Ratten wachsendes, transplantiertes Jensen-Sarkom geht einher mit einer Abnahme der Mastzellen in seiner Umgebung. Dabei treten in den Mastzellen Degranulierungen und Granulaverklumpungen auf. Nach anderen Transplantaten waren diese Veränderungen weniger ausgesprochen.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Burton, A. L.: Studies on living normal mast cells. Ann. N. Y. Acad. Sci. 103, 245–263 (1963).Google Scholar
  2. Costâchel, O., L. Fadei, and M. Nachtigal: The action of heparin in vitro on Syrian-Hamster sarcoma-cell culture. Exp. Cell Res. 34, 542–547 (1964).Google Scholar
  3. Csaba, P., T. Acs, C. Horwath, and K. Mold: Genesis and function of mast cells. Mast cells and plasmocyte reaction to induced, homologous and heterologous tumors. Brit. J. Cancer 15, 327–335 (1961).Google Scholar
  4. Gustafsson, B. E., and S. Cronberg: Comparison of the effects of compound 48/80, protamine and turpentine oil on mast-cell degranulation. Acta rheum. scand. 3, 189–202 (1957).Google Scholar
  5. McGovern, V. J.: The mechanism of inflammation. J. Path. Bact. 73, 99–106 (1957).Google Scholar
  6. Padawer, J.: Quantitative studies with mast cells. Ann. N. Y. Acad. Sci. 103, 87–137 (1963).Google Scholar
  7. Riley, J. F.: The mast cells. Edingburgh and London: E. & Livingstone LTD 1959.Google Scholar
  8. Scott, K. G.: The mast cell, its amines, and tumor growth in rodents and man. Ann. N.Y. Acad. Sci. 103, 285–309 (1963).Google Scholar
  9. R. R. Scheline, and R. S. Stone: Mast cells and sarcoma growth in the rat. Cancer Res. 18, 927–931 (1958).Google Scholar
  10. Simpson, W. L.: Distribution of mast cells as a function of age and exposure to carcinogenic agents. Ann. N. Y. Acad. Sci. 103, 4–18 (1963).Google Scholar
  11. Smith, D. E.: The tissue mast cell. Int. Rev. Cytol. 14, 328–386 (1963).Google Scholar
  12. Sylvén, B.: Ester sulphuric acids of high molecular weight and mast cells in mesenchymal tumours. Acta radiol. (Stockh.) (Suppl.) 59, 1–99 (1945).Google Scholar
  13. Uvnäs, B.: Release processes in mast cells and their activation by injury. Ann. N. Y. Acad. Sci. 116, 880–890 (1964).Google Scholar

Copyright information

© Springer-Verlag 1965

Authors and Affiliations

  • O. Costâchel
    • 1
  • Mironescu
    • 1
  • N. Stroescu
    • 1
  1. 1.Laboratory of Cellular BiologyInstitute of Oncology BucharestRumania

Personalised recommendations