Skip to main content
SpringerLink
Log in

Einfluß anisotonischer Lösungen auf die Überimpfbarkeit von Tumorzellen

  • Published:
Zeitschrift für Krebsforschung Aims and scope Submit manuscript

Summary

We examined the influences of different spheres of temperature on cellular suspensions of the solid Ehrlich-Carcinoma in isotonic and anisotonic solutions.

The most favourable sphere of temperature for the preservation of tumour cells in these mediums was observed between +2° and +4° C.

Cells of the Ehrlich-Carcinoma swollen in distilled water proved at the temperatures we examined (−10°, −20° and −30°C) to be more sensible towards the influence of the cold than shrunken cells or cells with physiological water contents. At the temperature of body only tumour cells suspended in isotonic solution could be inoculated successfully.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Lettré, H.: Über das Verhalten von Bestandteilen von Tumorzellen bei der Transplantation. V. Mitt. Gemische von granulafreien Zellen und Plasmagranula. Z. Krebsforsch. 57, 661–664 (1951).

    Google Scholar 

  2. Frohberg, H., u. G. Benad: Über den Einfluß von destilliertem Wasser und hypertonischen Lösungen auf das Ehrlich-Carcinom der Maus. Naturwiss.42, 348 (1955).

    Google Scholar 

  3. Frohberg, H., E. Matthies u. G. Benad: Vergleichende Tiefkühlversuche mit dem Brown-Pearce-Tumor des Kaninchens, dem Jensen-Sarkom der Ratte, dem Ehrlich-Carcinom der Maus und dem Yoshida-Sarkom der Ratte. Z. Krebsforsch. 60, 546–552 (1955).

    Google Scholar 

  4. Craigie, J.: A quantitative approach to the study of transplantable tumours. Brit. Med. J. 1949, No 4643, 1485–1491.

  5. Craigie, J.: Survival and preservation of tumours in the frozen state. Adv. Canc. Res. 1, 197–228 (1954).

    Google Scholar 

  6. Haagen, F., u. P. G. Seeger: Arbeiten am Tumorascites der Maus. IV. Mitt. Die Abhängigkeit der Übertragbarkeit des Tumorascites von der Vitalität der Zellen und von der Temperatur. Z. Krebsforsch. 47, 394–412 (1938).

    Google Scholar 

  7. Luyet, B. J., and P. M. Gehenio: The mechanism of injury and death by low temperature. A Review. Biodynamica 3, 33–99 (1940).

    Google Scholar 

  8. Breedis, C.: Zit. nach J. Craigie, Survival and preservation of tumours in the frozen state. Adv. Canc. Res. 1, 197–228 (1954).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pharmakologischen Institut der Martin-Luther-Universität Halle a. d.S., Halle a. d. S., Deutschland

    H. Frohberg, G. Benad & H. Bekemeier

Authors
  1. H. Frohberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Benad
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Bekemeier
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Frohberg, H., Benad, G. & Bekemeier, H. Einfluß anisotonischer Lösungen auf die Überimpfbarkeit von Tumorzellen. Z Krebs-forsch 61, 463–467 (1957). https://doi.org/10.1007/BF00524624

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00524624

Search

Navigation