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On the unimpairable resistance of the guinea pig to dietary amino azo dye hepatocarcinogenesis

Die Resistenz des Meerschweinchens gegenüber der hepatocarcinogenen Wirkung von gefütterten Amino-Azo-Farbstoffe

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Zusammenfassung

Die Resistenz des Meerschweinchens gegenüber der hepatocarcinogenen Wirkung von 3′-Methyl-4-dimethylaminoazobenzene, das mit 0,12% insgesamt 8 Monate gefüttert wurde, wird auch durch den starken co-carcinogenen Einfluß einer Partialhepatektomie nicht gebrochen.

Summary

The resistance of the guinea pig to carcinogenesis by 3′-methyl-4-dimethylaminoazobenzene fed at the level of 0.12% for a total of 8 months is not overcome by the potent cocarcinogenic influence of partial hepatectomy performed at 4 weeks.

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Author notes

  1. H. H. Gosch

    Present address: Section of Neurosurgery, Dept. of Surgery, Univ. of Michigan Medical School, Ann Arbor, Mich., USA

Authors and Affiliations

  1. Seamen's Memorial Research Laboratory, US Public Health Service Hospital, 210 State Street, 70118, New Orleans, Louisiana, (USA)

    H. H. Gosch, J. C. Arcos & M. F. Argus

  2. Department of Medicine (Biochemistry), Tulane University School of Medicine, New Orleans

    H. H. Gosch, J. C. Arcos & M. F. Argus

Authors
  1. H. H. Gosch
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  2. J. C. Arcos
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  3. M. F. Argus
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Additional information

Supported by Research Grant CA-05431 from the National Cancer Institute, United States Public Health Service.

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Gosch, H.H., Arcos, J.C. & Argus, M.F. On the unimpairable resistance of the guinea pig to dietary amino azo dye hepatocarcinogenesis. Z Krebs-forsch 73, 215–217 (1970). https://doi.org/10.1007/BF00524400

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  • DOI: https://doi.org/10.1007/BF00524400

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