Skip to main content
Log in

Die Inaktivierung des Rous-Sarkoms mittels eines kationischen Detergens

  • Published:
Zeitschrift für Krebsforschung Aims and scope Submit manuscript

Summary

The cationic detergent (cetyl-trimethyl-ammonium-bromide) (“Cetavlon”), when added to an extract of Rous sarcoma in vitro, has an inhibiting effect on the development of tumors even at low concentrations, (0.01%). Mostly no tumor develops, seldom a nodule of lentile seed size.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Pentimalli, F.: Agenti carcinogeni transmissibili. Acta Union, internat. contra Canc. 1936.

  2. Pentimalli, F.: L'agente del sarcoma dei polli è una virus-proteina. Settimana Med. 35, 176 (1947).

    Google Scholar 

  3. Kertész, D.: Inattivazione dell'agente del sarcoma di Rous per mezzo del sistema polifenolossidasico (Tirosinasi). Tumori 37, 481 (1951).

    Google Scholar 

  4. Kertész, D., e G. Cardinali: Azione del sistema polifenolossidasi-catecolo su colture in vitro di sarcoma di Rous. Tumori 38, 13 (1952).

    Google Scholar 

  5. Helmer, O. M., and G. H. A. Clowes: Effect of fatty acid structure on inhibition of growth of chicken sarcoma. Amer. J. Cancer 30, 553 (1937).

    Google Scholar 

  6. Nakajima, H., and W. Nakahara: Cataphoresis experiments on the filterable agent of Rous chicken sarcoma. Gann (jap.) 26, 181 (1952).

    Google Scholar 

  7. Lewis, M. R., and W. R. Lewis: Further studies on the inactivation of tumor-producing viruses by means of dyes. Amer. J. Canc. 16, 333 (1932).

    Google Scholar 

  8. Shemin, D., E. E. Sproul and J. W. Jobling: Studies on the trasmissible agent of the Rous chicken sarkoma I. Precipitation with basic proteins. J. of Exper. Med. 72, 697 (1940).

    Google Scholar 

  9. Caselli, P., e H. Schumacher: Inibizione dello sviluppo del sarcoma di Rous nella cornea e nel derma di pollo, a mezzo di proteine basiche. Boll.Ocul. 34, 513 (1955).

    Google Scholar 

  10. Jones, A. S.: The isolation of bacterial nucleic acids using cetyl-trimetil-ammonium bromide (Cetavlon). Biochim et Biophysica Acta 10, 607 (1953).

    Google Scholar 

  11. Pentimalli, F., e G. Schmidt: Über das Verhalten der Phosphorfractionen im Blutplasma sarkomkranker Hühner. Biochem. Z. 282 62 (1935).

    Google Scholar 

  12. Caselli, P.: Spettro ultravioletto di una frazione proteica, altamente infettiva, precipitabile con solfato d'ammonio da estratti acquosi di Sarcoma di Rous. Tumori 27, 125 (1953).

    Google Scholar 

  13. Caputo, A.: Comportamento elettroforetico di estratti di sarcoma di Rous sottoposti ad ultracentrifugazione.Tumori 41, 194 (1955).

    Google Scholar 

  14. Murphy, J. B., E. Sturm, A. Claude and O. M. Helmer: Properties of the causative agent of a chicken tumor. III. Attempts at isolation of the active principle. J. of Exper. Med. 56, 91 (1932).

    Google Scholar 

  15. Pentimalli, F.: Sulla natura dell'agente del sarcoma dei polli. Rend. Accad. ital. 1, 215 (1940).

    Google Scholar 

  16. Pentimalli, F.: Adsorption des Hühnersarkomagens durch die Erythrozyten und das Hämoglobin, in vitro. Verh. dtsch. Z. Ges. 118, 253 (1945).

    Google Scholar 

  17. Findlay, G. M.: The electrical charge of the virus of Fowl-pox and the agent of the Rous sarcoma. Brit. J. Exper. Path. 11, 190 (1930).

    Google Scholar 

  18. Pulcher, C.: Über die Adsorption des Roussarkomvirus seitens elektropositiven und elektronegativen Hämoglobins. Z. Krebsforsch. 32, 327 (1930).

    Google Scholar 

  19. Pirie, A.: Effect of lisozym on union between phage and susceptible bacillus megatherium. Brit. J. Exper. Path. 21, 125 (1940).

    Google Scholar 

  20. Puck, T. F., A. Garen and J. Cline: The mechanism of virus attachment to host cells. I. The role of ions in the primary reaction. J. of Exper. Med. 93, 65 (1951).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Mit 2 Textabbildungen

Rights and permissions

Reprints and permissions

About this article

Cite this article

Guerritore, D. Die Inaktivierung des Rous-Sarkoms mittels eines kationischen Detergens. Z Krebs-forsch 61, 649–654 (1957). https://doi.org/10.1007/BF00524390

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00524390

Navigation