Skip to main content
SpringerLink
Log in

Entwicklung und Verhalten eines Rattensarkoms während 5jähriger Züchtung in der Gewebekultur

  • Published:
Zeitschrift für Krebsforschung Aims and scope Submit manuscript

Summary

The spontaneous development of morphologically distinguishable substrains of a rat sarcoma in vitro is reported. After about 3 years of cultivation in vitro, cultures of these substrains were reimplanted into rats and samples of the resulting tumors were again explanted. The different morphology of the several substrains is described, as well as their differential response to mitotic poisons.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Berman, L., and C. S. Stulberg: Eight culture strains (Detroit) of human epithelial-like cells. Proc. Soc. exp. Biol. (N.Y.) 92, 730–735 (1956).

    Google Scholar 

  2. Berman, L., C. S. Stulberg and F. H. Ruddle: Human cell culture. Morphology of Detroit strains. Cancer Res. 17, 668–676 (1957).

    PubMed  Google Scholar 

  3. Fjelde, A.: Observations on a human tumour in tissue culture. Nature (Lond.) 175, 434 (1955).

    Google Scholar 

  4. Gropp, A., u. R. Lettré: Über adaptive Veränderungen der morphologischen Eigenschaften eines Mammacarcinoms der Maus. Z. Krebsforsch. 62, 616–635 (1959).

    PubMed  Google Scholar 

  5. Lettré, H.: Eigenschaftsänderungen von Tumorzellen. Z. Krebsforsch. 59, 568–580 (1953).

    PubMed  Google Scholar 

  6. Khanolkar, V. R., K. J. Ranadive, C. V. Bapat and S. G. Gangal: A cell strain of human lipogenic sarcoma cultivated in vitro. Indian J. Path. Bact. 1, 1–10 (1958).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Chemotherapeutischen Laboratorium der Farbwerke Hoechst AG. vormals Meister Lucius & Brüning, Frankfurt a. M.

    Ingeborg Hilwig

Authors
  1. Ingeborg Hilwig
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Mit 25 Textabbildungen

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hilwig, I. Entwicklung und Verhalten eines Rattensarkoms während 5jähriger Züchtung in der Gewebekultur. Zeitschrift für Krebsforschung 63, 222–231 (1960). https://doi.org/10.1007/BF00524355

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00524355

Search

Navigation