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Swelling of normal, preneoplastic and neoplastic liver mitochondria

II. The swelling of liver mitochondria from mice and rats fed carcinogenic azo dyes, and of hepatoma mitochondria

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References

  • Arcos, J. C., and M. Arcos: Fine-structural alterations in cell particles during chemical carcinogenesis. I. Influence of the feeding of aminoazo dyes on the swelling and solubilization of rat-liver microsomes. Biochim. biophys. Acta 28, 9 (1958).

    Google Scholar 

  • Arcos, J. C., G. W. Griffith and R. W. Cunningham: II. Further evidence for their involvement in the mechanism of carcinogenesis. The swelling of rat liver mitochondria during feeding of amino azo dyes. J. biophys. biochem. Cytol. 7, 49 (1960).

    Google Scholar 

  • Bernhard, W.: Die Anwendung des Elektronenmikroskopes zum Studium cellular-pathologischer Vorgänge. Klin. Wschr. 35, 251 (1957).

    Google Scholar 

  • Bernhard, W.: Electron Microscopy of tumor cells and tumor viruses. Cancer Res. 18, 491 (1958).

    Google Scholar 

  • Clerici, E., and G. Cudkowicz: Certain effects of p-dimethyl-aminoazobenzene, deficient diet, and hypotonic media on mitochondrial enzymes in experimental rat-liver carcinogenesis. J. nat. Cancer Inst. 16, 1459 (1956).

    Google Scholar 

  • Danielli, J. F.: The cell-to-cell transfer of nuclei in amoebae and a comprehensive cell theory. Ann. N.Y. Acad. Sci. 78, 675 (1959). [Compare: Nature (Lond.) 176, 1114 (1955); J. cell. comp. Physiol. 52, Suppl. 1, 51 (1958).]

    Google Scholar 

  • Emmelot, P.: Effects of hepatic carcinogens on isolated liver mitochondria. Acta Un. int. Cancr. 14, 50 (1958).

    Google Scholar 

  • Emmelot, P., and C. J. Bos: The effect of thyroxine on the swelling of mitochondria isolated from normal and neoplastic livers. Exp. Cell Res. 12, 191 (1957a).

    Google Scholar 

  • Emmelot, P., and C. J. Bos: Effects shown by hepatocarcinogens on isolated liver mitochondria. Biochim. biophys. Acta 24, 442 (1957b).

    Google Scholar 

  • Emmelot, P., and C. J. Bos: Thyroxine-mediated release of diphosphopyridine nucleotide from mitochondrial dehydrogenases. Exp. Cell Res. 14, 132 (1958).

    Google Scholar 

  • Emmelot, P., C. J. Bos, P. J. Brombacher and J. F. Hampe: Studies on isolated tumor mitochondria. Biochemical properties of mitochondria from hepatomas with special reference to a transplanted rat hepatoma of the solid type. Brit. J. Cancer 13, 348 (1959).

    Google Scholar 

  • Emmelot, P., C. J. Bos and I. H. M. Reyers: Z. Krebsforsch. 64 (1960).

  • Emmelot, P., and G. H. van Vals: The metabolism of neoplastic tissues: The metabolic activity of normal and cancerous rat livers studied with acetate-I-14C in vitro. Z. Krebsforschg. 62, 116 (1957).

    Google Scholar 

  • Ernster, L., and H. Löw: Reconstruction of oxidative phosphorylation in aged mitochondrial systems. Exp. Cell Res., Suppl. 3, 133 (1955).

    Google Scholar 

  • Howatson, A. F., and A. W. Ham: Electron microscope study of sections of two rat liver tumors. Cancer Res. 15, 62 (1955).

    Google Scholar 

  • Howatson, A. F., and A. W. Ham: The fine structure of normal and malignant cells as revealed by the electron microscope. Canad. Cancer Conference 2, 17 (1956).

    Google Scholar 

  • Kielley, R. K.: Inhibitory effect of some aminoazo dyes and other carcinogens on glutamate oxidation on mitochondria of riboflavin-deficient rat liver. J. nat. Cancer Inst. 19, 1077 (1957).

    Google Scholar 

  • Laird, A. K., and A. D. Barton: Cell growth and the development of tumours. Nature (Lond.) 183, 1655 (1959).

    Google Scholar 

  • Lehninger, A. L.: In: Enzymes: Units of biological structure and function (O. H. Gaebler ed.), p. 217. New York: Academic Press, Inc. 1956.

    Google Scholar 

  • Löw, H.: On the participation of flavin in mitochondrial adenosine triphosphatase reactions. Biochim. biophys. Acta 32, 1 (1959).

    Google Scholar 

  • Man, J. C. H. de: Observations, with the aid of the electron microscope, on the mitochondrial structure of experimental liver tumors in the rat. J. nat. Cancer Inst. 24, 795 (1960).

    Google Scholar 

  • Porter, K. R., and C. B. Bruni: An electron microscope study of the early effects of 3′-Me-DAB on rat liver cells. Cancer Res. 19, 997 (1959).

    Google Scholar 

  • Tapley, D. F.: The effect of thyroxine and other substances on the swelling of isolated rat liver mitochondria. J. biol. Chem. 222, 325 (1956).

    Google Scholar 

  • Tujimara, H.: Electron microscopic studies on the DAB-induced hepatoma. Med. J. Osaka Univ. 9, 135 (1958).

    Google Scholar 

  • Weissenfels, N.: Über die Entleerung und Entwicklung der Mitochondrien und den Feinbau des Cytoplasmas von embryonalen Zellen. Z. Naturforsch. 13b, 182 (1958).

    Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, Antoni van Leeuwenhoek-Huis, The Netherlands Cancer Institute, Amsterdam, The Netherlands

    P. Emmelot & I. H. M. Reyers

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  1. P. Emmelot
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  2. I. H. M. Reyers
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Emmelot, P., Reyers, I.H.M. Swelling of normal, preneoplastic and neoplastic liver mitochondria. Z Krebs-forsch 64, 35–51 (1960). https://doi.org/10.1007/BF00524275

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