Summary
In 67 healthy prematures the actual pH, the actual pCO2, the standard bicarbonate and the base excess have been examined by the Astrup method. The examinations were done at the first day of life, partly also during the following 4 days.
The most marked shift in the acid-base equilibrium occurs during the first 4 hours of life. The respiratoric acidosis was compensated after 4 hours, the metabolic acidosis during the first 24 hours. From the 2. to the 5. day of life there were no marked disturbances in the acid-base metabolism.
For prophylaxis and therapy of the respiratory distress syndrome the acid-base metabolism of all prematures should be examined during the first days of life as a routine.
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Ausführliche Darstellung: R. Kellner, Inauguraldissertation, Rostock 1966.
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Kellner, R. Untersuchungen über die postnatale Regulation des Säure-Basen-Stoffwechsels bei gesunden Frühgeborenen. Z. Kinder-Heilk. 97, 299–314 (1966). https://doi.org/10.1007/BF00523280
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DOI: https://doi.org/10.1007/BF00523280