Abstract
The reactions of 4,5-dinitroimidazole and 5(4)-nitroimidazole-4(5)-sulfonic acid with nucleophilic agents were studied. Mercapto-, alkoxy-, and aminonitroimidazoles were synthesized. In the reaction of dinitroimidazole with sodium alkoxides 5(4)-nitroimidazole was obtained in addition to alkoxynitroimidazoles. It is shown that in the formation of salts of the starting imidazoles with bases nucleophilic-substitution reactions take place only with “soft” reagents.
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Translated from Khimiya Geterotsiklicheakikh Soedinenii, No. 6, pp. 808–810, June, 1983.
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Mokrushin, V.S., Belyaev, N.A., Kolobov, M.Y. et al. Reactions of 4,5-dinitroimidazole and 4(5)-nitroimidazole-5(4)-sulfonic acid with nucleophiles. Chem Heterocycl Compd 19, 650–652 (1983). https://doi.org/10.1007/BF00523079
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DOI: https://doi.org/10.1007/BF00523079