Abstract
The reaction of 5-amino-6-mercaptopyrimidine and 2-mercapto-3-aminopyridine with esters of β-chloro-α,γ-diketo acids, leads, depending on the pH, to the formation of three-ring and two-ring 1,4-thiazine systems. A preparative method for the production of previously unknown 6-carbethoxy-7-acyl-5H-pyrimido[4,5-b]- and 6-carbethoxy-7-acyl-5H-pyrido[2,3-b]-l,4-thiazines was developed.
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See [1] for Communication 39.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 772–775, June, 1983.
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Levkovskaya, L.G., Mamaeva, I.E., Serochkina, L.A. et al. Investigation of nitrogen- and sulfur-containing heterocycles. 40. 6-Carbethoxy-7-acyl-5H-pyrimido[4,5-b]- and 6-carbethoxy-7-acyl-5H-pyrido[2,3-b]-1,4-thiazines. Chem Heterocycl Compd 19, 618–621 (1983). https://doi.org/10.1007/BF00523072
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DOI: https://doi.org/10.1007/BF00523072