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Chemistry of Heterocyclic Compounds

, Volume 6, Issue 12, pp 1495–1497 | Cite as

Alkyl- and arylamination of 3-hydroxy-4-carbethoxy-5-methylthiophene

  • V. I. Shvedov
  • V. K. Vasil'eva
  • A. N. Grinev
Article

Abstract

N-Alkylaminothiophene derivatives were obtained by the reaction of 3-hydroxy-4-carbethoxy-5-methylthiophene with alkylammonium acetates, while N-arylaminothiophene derivatives were obtained by the reaction of the same thiophene derivative with aromatic amines in the presence of catalytic amounts of iodine.

Keywords

Acetate Organic Chemistry Iodine Thiophene Aromatic Amine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1973

Authors and Affiliations

  • V. I. Shvedov
    • 1
  • V. K. Vasil'eva
    • 1
  • A. N. Grinev
    • 1
  1. 1.S. Ordzhonidze All-Union Scientific-Research Institute of Pharmaceutical ChemistryMoscow

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