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Impulscytophotometrie der DNS in Hauttumoren

Pulse cytophotometry of DNA in skin tumours

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Summary

In eight samples of skin tumours a greater number of nuclei with an increased DNA content as compared to controls (normal skin, lymph nodes and periglottis) were found by pulse cytophotometry. DNA histograms—each histogram representing 50.000–200.000 nuclei—are predominantly in good correlation with the clinical and histological findings.

With the new method of pulse cytophotometry it is possible to obatin DNA histograms of a great number of tumours in a short time with a high degree of accuracy.

Zusammenfassung

Die Impulscytophotometrie ermittelte bei 8 Hauttumoren einen höheren Anteil von Zellkernen mit erhöhtem DNS-Gehalt als bei Kontrollgeweben (Vollhaut, Lymphknoten und Zengenschleimhaut). Die DNS-Histogramme, welche jeweils 50000–200000 Zellkerne repräsentieren, korrespondierten in wesentlichen Einzelheiten den klinischen und histologischen Befund.

Das neuartige Meßverfahren der Impulscytophotometrie erlaubt bei großer Genauigkeit jeder einzelnen Messung wegen der hohen Geschwindigkeit des Meßablaufs Untersuchungen an einer Vielzahl von Tumoren in kürzester Zeit.

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Authors and Affiliations

  1. Fachklinik „Haus Hornheide” des Westfälischen Vereins für Krebs- und Lupusbekämpfung, Handorf/Münster

    J. Schumann, F. Ehring, W. Göhde & W. Dittrich

  2. Institut für Strahlenbiologie der Westfälischen Wilhelms-Universität, Münster

    J. Schumann, F. Ehring, W. Göhde & W. Dittrich

Authors
  1. J. Schumann
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  2. F. Ehring
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  3. W. Göhde
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  4. W. Dittrich
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Schumann, J., Ehring, F., Göhde, W. et al. Impulscytophotometrie der DNS in Hauttumoren. Arch. klin. exp. Derm. 239, 377–389 (1971). https://doi.org/10.1007/BF00520091

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  • DOI: https://doi.org/10.1007/BF00520091

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