Chemistry of Heterocyclic Compounds

, Volume 21, Issue 8, pp 891–895 | Cite as

Derivatives of aziridine-1,2-dicarboxylic acid

  • P. T. Trapentsier
  • I. Ya. Kalvin'sh
  • É. É. Liepin'sh
  • É. Ya. Lukevits
  • V. Ya. Kauss
Article

Abstract

The corresponding esters and amides of aziridine-1,2-di-carboxylic acid were obtained by the reaction of esters and amides of aziridine-2-carbocylic acid with esters and amides of chlorocarbonic acid, isocyanates, and isothiocyanates. The reaction of 2-methoxycarbonylaziridine with diisocyanates and chlorides of the dicarboxylic acids leads to the formation of bisaziridines.

Keywords

Chloride Ester Organic Chemistry Amide Isothiocyanates 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    M. Von Ardenne and P. G. Reitnauer, Arzneimittel Forsch., Drug Res., 27, 1701 (1977).Google Scholar
  2. 2.
    I. Ya. Kalvin'sh and E. B. Astapenok, Belgian Patent No. 860239; Chem. Abstr., 90, 34103 (1979).Google Scholar
  3. 3.
    G. A. Luckenbach, D. Cortecampeao, M. L. Modolell, P. G. Munder, and U. Bicker, Exp. Pathol., 19, 37 (1981).Google Scholar
  4. 4.
    J. Cheymol, P. Chabrier, G. Deysson, and A. Carayon-Gentil, Biol. Med. (Paris), 56, 519 (1967).Google Scholar
  5. 5.
    C. W. Woods, A. B. Borkovec, and F. M. Hart, J. Med. Chem., 7, 371 (1964).Google Scholar
  6. 6.
    E. Bosies, R. Heerdt, R. Gall, U. Bicker, and A. E. Ziegler, West German Patent No. 2656323; Chem. Abstr., 91, 39299 (1980).Google Scholar

Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • P. T. Trapentsier
    • 1
  • I. Ya. Kalvin'sh
    • 1
  • É. É. Liepin'sh
    • 1
  • É. Ya. Lukevits
    • 1
  • V. Ya. Kauss
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga

Personalised recommendations