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Preliminary Observations about the Ultrastructure of the Human Nail Plate Treated with Thioglycolic Acid

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Zusammenfassung

Verfasser beschreiben die Ultrastruktur der Lamina unguinalis und weisen nach, daß die Kompaktheit ihrer Zellen folgenden Faktoren zuzuschreiben ist:

  1. 1.

    Durch den Prozeß der Keratinisierung und Dehydratation hervorgerufenes Ineinanderfügen der Zellen.

  2. 2.

    Anzahl der Bindungen.

  3. 3.

    Struktur der Bindungen (in der Art der “type junction”, der “intermediate junction” und der “desmosome-like junction”).

Summary

The authors describe the ultrastructure of the nail plate cells and demonstrate that their compactness is governed by:

  1. 1.

    “dove-tailing” which the keratinization and dehydration process caused between one cell element and the next.

  2. 2.

    the number of links.

  3. 3.

    the structure of the links (tight junction type, intermediate junction type, desmosome-like type).

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References

  1. Achten, G.: L'ongle normal et pathologique. Dermatologica (Basel) 126, 229–245 (1963).

    Article  CAS  Google Scholar 

  2. Brody, I.: The keratinization of epidermal cells of normal guinea pig skin as revealed by electron microscopy. J. Ultrastruct. Res. 3, 482–511 (1959).

    Article  Google Scholar 

  3. —: The ultrastructure of the horny layer in normal and psoriatic epidermis as revealed by electron microscopy. J. invest. Derm. 39, 519–527 (1962).

    Article  CAS  PubMed  Google Scholar 

  4. Caputo, R., and L. Lombardi: Quadri ultrastrutturali dell'epidermide umana normale. Atti Accad. med. lombarda 18, 72–77 (1963).

    Google Scholar 

  5. Hashimoto, K., B. Gross, R. Nelson, and F. Lever: The ultrastructure of the skin of human embryos. III. The formation of the Nail in 16–18 Weeks Old embryos. J. invest. Derm. 47, 205–217 (1966).

    Article  CAS  PubMed  Google Scholar 

  6. Millonig, G.: Further observations on a phosphate buffer for osmium solution. Proc. 5th Intern. Congr. of Electron Microscopy Philadelphia, p. 8. New York: Acad. Press 1962.

    Google Scholar 

  7. Rogers, G. E.: Electron microscope studies of the hair and wool. Ann. N. Y. Acad Sci. 83, 378–407 (1959).

    Article  CAS  PubMed  Google Scholar 

  8. Snell, R. S.: Intercellular debris in the stratum corneum of the human epidermis. J. invest. Derm. 47, 598–602 (1966).

    Article  CAS  PubMed  Google Scholar 

  9. Zelickson, A. S.: Normal human keratinization processes as demonstrated by electron microscopy. J. invest. Derm. 37, 369–379 (1961).

    Article  CAS  PubMed  Google Scholar 

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Caputo, R., Dadati, E. Preliminary Observations about the Ultrastructure of the Human Nail Plate Treated with Thioglycolic Acid. Arch. klin. exp. Derm. 231, 344–354 (1968). https://doi.org/10.1007/BF00517687

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  • DOI: https://doi.org/10.1007/BF00517687

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