Summary
This study investigates the existence and course of psychomotor symptoms in schizophrenic patients (n = 57, both treated and untreated with antipsychotic drugs) as compared to 25 healthy controls. Previous psychometric studies had suggested the existence of a “psychotic motor syndrome” (PMS) both in (untreated) schizophrenic and endogenous depressed patients, consisting of disturbances of lip and tongue movements, fine and gross movements of the dominant right hand and impaired complex motor coordination of the extremities. We confirmed the existence of the PMS in this study. There was no correlation of the PMS with the psychopathological status of the patients, or with extrapyramidal side-effects of the drugs used, perhaps indicating an independent “basic syndrome” (“Basisstörung”). Factorial analyses revealed similar structures both in schizophrenic and healthy persons; the differences in motor performance may be due to an impairment of the first factor “general motor ability” in schizophrenic patients. The PMS did not disappear parallel to the psychopathological improvement of the patients, nor in the symptom-free remission interval. The role of the PMS as possible independent biological marker syndrome for schizophrenia can consequently be further supported, with its implications towards the differential diagnostic and therapeutical values of this syndrome.
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References
American Psychiatric Association (1980) DSM-III. APA, New York
Brodie JD, Wolf AP, Wolkin A, Arnett CD, Angrist B, Fowler J, Smith M, Russel J, Logan J, Christman D, Rotrosen J, Volkow N (1985) PET studies in schizophrenia. Abstracts 4th World Congr Biol Psychiatry, Philadelphia
Clauss H, Ebner G (1974) Grundlagen der Statistik. VEB Volk and Wissen, Berlin
Crow TJ, Corsellis JAN, Frith CD, Johnstone EC, Owen F, Bloxham CB, Ferrier IN, Owens DGC (1981). The search for changes underlying the type II syndrome in schizophrenia. In: Perris C, Struw G, Jansson B (eds) Biological psychiatry 1981. Elsevier, Amsterdam, pp 727–731
Dahl G (1972) WIP, Reduzierter Wechsler-Intelligenz-Test. Hain, Meisenheim
Degkwitz R, Helmchen H, Kockott G, Mombour W (1980) Diagnosenschlüssel und Glossar psychitrischer Krankheiten. Deutsche Ausgabe der internationalen Klassifikation der Krankheiten der WHO, ICD-9. Springer, Berlin Heidelberg New York
Endicott J, Spitzer RL (1978) A diagnostic interview: The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837–844
Fleishman EA (1954) Structure and measurement of psychomotor abilities. In: Singer RN (ed) The psychomotor domain: movement behavior. Pergamon Press, Philadelphia, pp 78–106
Flor-Henry P (1976) Lateralized temporal-limbic dysfunction and psychopathology. Ann NY Acad Sci 280:777–797
Golden CJ (1979) Clinical interpretation of objective psychological tests. Basic Books, New York
Gruzelier JH, Hammond N (1976) Schizophrenia: a dominant hemisphere temporal-limbic disorder. Res Commun Psychol Psychiatr Behav 1:33–72
Guenther W (1980) Untersuchungen zur Wirksamkeit mentaler Trainingsverfahren grobmotorischer Bewegungen bei der Rehabilitation zentralmotorisch Behinderter. Dissertation Tübingen
Guenther W (1984) Psychomotor training programs in the acute treatment and rehabilitation of schizophrenia. Abstracts WPA symposium on psychiatric rehabilitation, Rome
Guenther W, Gruber H (1983) Psychomotorische Störungen bei psychiatrischen Patienten als mögliche Grundlage neuer Ansätze in Differentialdiagnose und Therapie. I. Ergebnisse erster Untersuchungen an depressiven und schizophrenen Kranken. Arch Psychiatr Nervenkr 233:187–209
Guenther W, Breitling D (1985) Predominant sensorimotor area left hemisphere dysfunction in schyzophrenia measured by brain electrical activity mapping. Biol Psychiatry 20:515–532
Guenther W, Breitling D, Banquet JP, Marcie P, Rondot P (1986) EEG mapping of left hemisphere dysfunction during motor performance in schizophrenia. Biol Psychiatry 21:249–262
Guenther W, Moser E, Müller-Spahn, Oefele Kv, Buell U, Hippius H (1986) Pathological cerebral blood flow during motor function in schizophrenic and endogenous depressed patients. Biol Psychiatry (in press)
Gur RE, Skolnick BS, Gur RC, Caroff S, Rieger W, Obrist WD, Younkin D, Reivich M (1983) Brain function in psychiatric disorders: I. Regional cerebral blood flow in medicated schizophrenics. Arch Gen Psychiatry 40:1250–1254
Gur RC, Gur RC, Skolnick BE, Caroff S, Obrist WD, Resnick S, Reivich M (1985) Brain function in psychiatric disorders. III. Regional cerebral blood flow in unmedicated schizophrenics. Arch Gen Psychiatry 42:329–334
Iacono WG, Tuason VB, Johnson RA (1981) Dissociation of smoothpursuit and saccadic eye-tracking in remitted schizophrenics. Arch Gen Psychiatry 38:991–996
Latham C, Holzman PS, Manschreck TC, Tole J (1981) Optokinetic nystagmus and pursuit eye movements in schizophrenia. Arch Gen Psychiatry 38:997–1003
Lauritzen M, Henriksen L, Lassen NA (1981) Regional cerebral blood flow during rest and skilled hand movements by Xe-133 inhalation and emission computerised tomography. J Cerebr Blood Flow Metab 1:385–389
Lauria AR (1970) Die höheren kortikalen Funktionen des Menschen and ihre Störungen bei brtlichen Hirnschädigungen. VEB, Berlin
Manschreck TC, Maher BA, Rucklos BE, Vereen DR jr, Ader DN (1981) Deficient motor synchrony in schizophrenia. J Alm Psychol 90:321–328
Mather JA, Putchat C (1984) Motor control of schizophrenics - II. Manual control and tracking: sensory and motor deficits. J Psychiatr Res 18:287–298
Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 9:97–113
Oseretzky N (1931) Psychomotorik. Methoden zur Untersuchung der Motorik. Z Angew Psychol 57: Beih. 1
Overall JE, Gorham DR (1976) Brief Psychiatric Rating Scale. In: Guy W (ed) ECDEU Assessment manual for psychopharmacology. Rockville, Bethesda MD, pp 157–169
Reinert G (1966) Entwicklungstests. In: Heiss R (ed) Handbuch der Psychologie, Bd 6. Hogrefe, Göttingen, pp 315–321
Schoppe KJ (1974) Das M-L-S Gerät. Ein neuer Testapparat zur Messung feinmotorischer Leistung. Diagnostica 20:43–46
Simpson GH, Angus JWS (1970) A rating scale for extrapyramidal side effects. Acta Psychiatr Scand (Suppl) 212:11–19
Spitzer RL, Endicott J, Robins E (1977) Research Diagnostic Criteria for a selected group of functional disorders. Biometric Research Division, New York State Psychiatric Institute
Steinberg R, Raith L (1986) Music psychopathology. I. Musical tempo and psychiatric disease. Psychopathology (in press)
Stender B, Marschner G (1972) Revisions-Test. Hogrefe, Göttingen
Suellwold L (1977) Symptome schizophrener Erkrankungen. Springer, Berlin Heidelberg New York
Thams PF (1955) Factor analysis of the Lincoln-Oseretzky Motor Development Scale. MD Thesis, Michigan
Webster DD (1968) Critical analysis of disability in Parkinson's disease. Mod Treatm 5:257–282
Wulfeck WH (1941) Motor function in the mentally disordered. 1. A comparative investigation of motor function in psychotics, psychoneurotics and normals. Psychol Rev 4:271–323
Yates AJ (1973) Abnormalities of psychomotor function. In: Eysenck HJ (ed) Handbook of abnormal psychology. Pitman, London, pp 261–283
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Supported in part by the Deutsche Forschungsgemeinschaft (DFG Gu 207/2-1).
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Günther, W., Günther, R., Eich, F.X. et al. Psychomotor disturbances in psychiatric patients as a possible basis for new attempts at differential diagnosis and therapy. Eur Arch Psychiatr Neurol Sci 235, 301–308 (1986). https://doi.org/10.1007/BF00515918
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DOI: https://doi.org/10.1007/BF00515918