Abstract
The chlorination of 1,8-dimethyl-7-phenylimidazo[1,2-f]xanthine with an equimolar amount of PCl5 in POCl3 leads to 2,4-dichloro-8-methyl-7-phenylimidazo[1,2-f]-purine. The possibility of substitution of the halogen atoms in reactions with nucleophilic reagents to give various 4-amino and 2,4-diamino derivatives was studied.
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See [1] for Communication 4.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 407–412, March, 1984.
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Garmash, S.N., Priimenko, B.A., Klyuev, N.A. et al. Heterocyclic derivatives of purines. 5. Nucleophilic substitution in series of imidazo[1,2-f]purine derivatives. Chem Heterocycl Compd 20, 330–334 (1984). https://doi.org/10.1007/BF00515651
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DOI: https://doi.org/10.1007/BF00515651