Abstract
The reactions of 4-chloroimidazo[4,5-d]-1,2,3-triazine with a number of nucleophilic reagents have been studied. Either replacement of the chlorine atom in position 4 of the 1,2,3-triazine ring or opening of the triazine ring with the formation of products of the interaction of the intermediate 5-diazoimidazole-4-carbonitrile with these nucleophiles occurs, depending on the nucleophilicity of the reagent.
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For Report 11, see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1548–1551, November, 1983.
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Mokrushin, V.S., Pospelova, T.A. & Shafran, Y.M. Synthesis and properties of analogs of 5(or 4)-aminoimidazole-4(or 5)-carboxamide (aica) and purines. 12. Investigation of the interaction of 4-chloroimidazo[4,5-d]-1,2,3-triazine with nucleophiles. Chem Heterocycl Compd 19, 1231–1234 (1983). https://doi.org/10.1007/BF00515366
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DOI: https://doi.org/10.1007/BF00515366